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Serious side effects of alprazolam (Xanax)

Xanax without prescription UK


Toxic epidermal necrolysis
Severe allergic reaction (anaphylaxis)
Stevens-Johnson syndrome
Gastrointestinal bleeding
Kidney toxicity
Liver toxicity / liver failure
Low number of white blood cells (leukopenia, neutropenia)
Low platelet count (thrombocytopenia)
Low number of red and white blood cells and low number of platelets (pancytopenia)

Side effects of alprazolam (Xanax) from post-marketing reports:

Gastrointestinal: Increases in liver enzymes, hepatitis, liver failure
CNS: Hypomanie, manie
Immunological: Stevens-Johnson syndrome, skin swelling, limb swelling
Endocrine: increased blood prolactin, swelling of breast tissue in men (gynecomastia), milky nipple discharge that is not related to breastfeeding (galactorrhea)
This page does not contain all possible side effects and other serious side effects may occur. Contact your doctor for additional health information about common problems or adverse side effects with this medicine. Patients taking this medicine must not use alcohol.


If your doctor has instructed you to use this prescription medicine, your doctor or pharmacist may already be aware of possible drug interactions, health risks, and side effects and may be watching you. Do not start, stop or change the dose of this medication or any other medication before contacting your doctor, health care professional or pharmacist.
Serious interactions of alprazolam (Xanax) include:
  • itraconazole
  • ketoconazole
  • sodium oxybate
  • tipranavir

Serious interactions of alprazolam (Xanax) include:

  • carbamazepine
  • cimetidine
  • claritromycine
  • erytromycinebase
  • erytromycine ethylsuccinaat
  • erythromycin lactobionate
  • erytromycinestearaat
  • thereselibib
  • itraconazole
  • Ivacaftor
  • ketoconazole
  • nefazodon
  • rifabutine
  • rifampicine
  • saquinavir
  • St. John’s wort
  • Valerian
Alprazolam (Xanax) has moderate interactions with at least 264 different drugs.
Small interactions of alprazolam (Xanax) include:
  • brimonidine
  • ciprofloxacin
  • esomeprazole
  • eucalyptus
  • fleroxacin
  • gemifloxacine
  • green tea
  • levofloxacine
  • lithium
  • moxifloxacine
  • norfloxacine
  • ofloxacine
  • omeprazol
  • rifabutine
  • sage
  • vinpocetine
  • zolpidem


You will be calmer within a few hours of taking it. This lasts 8 to 12 hours. A sustained-release tablet can last up to 24 hours.
For anxiety, do not use for longer than a few weeks at a time. With social phobia or panic disorder you often have to use it for half a year or a year.
If you use alprazolam daily, you may become dependent on it. It is then difficult to stop using. Are you using it for more than a few weeks at a time? Then don’t stop all at once. Reduce slowly in consultation with your doctor or pharmacist.
You can get drowsy, sleepy or tired and your responsiveness diminishes. Do you use alprazolam every day? You are not allowed to drive. Do you use it occasionally? Then you may not drive for 3 days (72 hours) after each intake.

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